Fluphenazine-resistant Saccharomyces cerevisiae mutants defective in the cell division cycle

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Fluphenazine-resistant Saccharomyces cerevisiae mutants defective in the cell division cycle.

An fls1 mutant of Saccharomyces cerevisiae, which did not grow in the presence of 30 micrograms of fluphenazine per ml, was isolated. Mutants that were resistant to 90 micrograms of fluphenazine per ml and temperature sensitive for growth were obtained from the fls1 mutant. One fluphenazine-resistance mutation, fsr1, was located near the his7 locus on chromosome II. Growth of the fsr1 mutants a...

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Saccharomyces cerevisiae cell cycle.

INTRODUCTION ......................................... 164 SYNCHRONOUS CULTURES .................. ....................... 165 Assay of Landmarks ......... ................................ 165 Induction Synchrony .......... ............................... 166 Selection Synchrony 167 CELL DIVISION CYCLE MUTANTS ......................................... 167 Diagnostic Landmarks and Terminal Pheno...

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The selection of S. cerevisiae mutants defective in the start event of cell division.

Thirty-three temperature-sensitive mutations defective in the start event of the cell division cycle of Saccharomyces cerevisiae were isolated and subjected to preliminary characterization. Complementation studies assigned thes mutations to four complementation groups, one of which, cdc28, has been described previously. Genetic analysis revealed that these complementation groups define single n...

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Cell-Cycle Perturbations Suppress the Slow-Growth Defect of spt10Δ Mutants in Saccharomyces cerevisiae

Spt10 is a putative acetyltransferase of Saccharomyces cerevisiae that directly activates the transcription of histone genes. Deletion of SPT10 causes a severe slow growth phenotype, showing that Spt10 is critical for normal cell division. To gain insight into the function of Spt10, we identified mutations that impair or improve the growth of spt10 null (spt10Δ) mutants. Mutations that cause le...

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Glycolysis mutants in Saccharomyces cerevisiae.

Mutants have been isolated in S. cerevisiae with the phenotype of growth on pyruvate but not on glucose, or growth on rich medium with pyruvate but inhibition by glucose. Screening of mutagenized cultures was either without an enrichment step, or after enrichment using the antibiotic netropsin (Young et al. 1976) or inositol starvation (Henry, Donahue and Culbertson 1975). One class of mutants ...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1986

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.168.3.1352-1357.1986